Setting up virtual environments on python simplify development.
Consider also virtualenvwrapper and autoenv ad ons.
An excellent collection of Python resources for quantitative development maintained by the folks at Quantsoftware — http://wiki.quantsoftware.org/index.php?title=Resources
Creating a RESTful service with Python and Flask
Django on Google App Engine Part1 and Part2
Complete guide to packaging up your Python code
Structuring large Flask application
Flask Bones appears to be an awesome collection
Awesome restructured text viewer
Norm Matloff’s python tutorial, including his “quick and painless” python
A proposal for embedding R on the server side in Python. Example of a historical time series analysis on data (e.g., 60 day MA) with code in github